Giant Cell Fibroma in an Elderly Woman: A Report of a Rare, Late and Unusually Large Presentation

Unusually Large Giant Cell Fibroma


  • Remilekun T. OLUWAKUYIDE,
  • Babalola O. CASTANO
  • Abdulwarith O. AKINSHIPO
  • Adeshina O. AYODELE


Giant Cell, Fibroma, Maxilla, Histology, Nigerian


Giant cell fibroma (GCF) is a rare benign oral fibrous lesion which is predominantly found in the mandible of Caucasians but rarely in the maxilla and black population above the third decade of life.

Objective: To draw the attention of clinicians to a rare, late and unusually large presentation of Giant Cell Fibroma

Case report: The index case was a 68-year-old fisherwoman with a ten-year-old slow-growing painless swelling occupying the left anterior maxilla. The lesion crossed the midline to the right causing incompetent lips and teeth displacement leading to aesthetics and functional problems.
Upon clinical examination, a provisional diagnosis of peripheral giant cell granuloma was made. Radiological essentially revealed a soft tissue mass, histopathological evaluations confirmed the diagnosis of GCF and the patient was prepared for surgical excision. A surgical excision of the soft tissue mass and peripheral ostectomy was performed.

Conclusion: GCF has distinct histopathologic features occurring in any age, race, site and decades of life; growing very large causing aesthetics and functional problems. Immunohistochemistry if available is an additional resource to unequivocally establish the diagnosis.

Author Biographies


Department of Oral and Maxillofacial Pathology, Dental Clinic, General Hospital Lagos Island,

Babalola O. CASTANO

Department of Family Dentistry, Dental Clinic, General Hospital Lagos Island,

Abdulwarith O. AKINSHIPO

Department of Oral and Maxillofacial Pathology, College of Medicine University of Lagos, Idi-Araba, Lagos,

Adeshina O. AYODELE

Department of Oral and Maxillofacial Surgery, General Hospital Lagos Island.




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